How does the placebo effect work? A new study identifies the vlPAG brain region and endogenous opioid signaling as the keys to expectancy-driven pain relief.

No significant drug-related differences seen for clinical pain severity, thermal threshold or tolerance, general pain ...

A noninvasive, home-based brain treatment with transcranial direct current stimulation (tDCS) can reduce pain severity, improve pain-related disability, and enhance endogenous pain modulation in women ...

51.6 million Americans live with chronic pain. A new device created by USC biomedical engineers could help sufferers avoid the need for opioids. Image/Karolina Grabowska, Pexels. Chronic pain is a ...

Staying physically active improves pain modulation and reduces the risk of older adults developing chronic pain, according to new research by Kelly Naugle and colleagues at Indiana University-Purdue ...

NEW IBS research highlights persistent pain treatment gaps and points to peripheral nerve targets for future, safer therapies ...