Chemical modification of proteins enables the development of proteins with novel functions and properties and has industrial and pharmacological applications. Modified proteins can exhibit improved ...

N-terminal acetylation represents one of the most ubiquitous protein modifications in eukaryotic cells, with significant implications for protein stability, folding, and interactions. This covalent ...

A research team led by Purdue University’s W. Andy Tao (front) has discovered of a new type of protein modification related to cellular mutation that impairs a crucial enzyme’s ability to help drive ...

A research team led by Prof. Wang Yi and Wei Haiming from the University of Science and Technology of China (USTC), in collaboration with Prof. Ding Chen's team from Human Phenome Institute at Fudan ...

Virology researchers have found that a specific protein modification to the immune protein MDA5 is key to how our bodies detect and respond to viruses and viral replication. The publication explains ...

Scientists have pinpointed the enzyme YcaO as responsible for a rare ribosomal protein modification in several pathogenic bacteria, a process absent in humans. The finding could open new avenues for ...

STING" molecular switch drives Alzheimer's brain inflammation. Blocking this switch protects synapses in new study.

For years, ETH researchers have been investigating a molecular complex that plays a key role in protein synthesis. They have now discovered that this complex also contributes a crucial function in ...

A research team led by Professor Seung Soo Oh and Dr. Hyesung Jo from the Department of Materials Science and Engineering at POSTECH (Pohang University of Science and Technology) has developed an ...

Cleveland Clinic virology researchers have found that a specific protein modification to the immune protein MDA5 is key to how human bodies detect and respond to viruses and viral replication. This ...

(Nanowerk Spotlight) Protein-based nanomaterials that respond to light are emerging as candidates for integrating biological compatibility with programmable electronic behavior. Their appeal lies in ...

Researchers at Baylor College of Medicine have developed an artificial intelligence (AI) model that reveals how protein modifications link genetic mutations to disease. The method, called DeepMVP and ...